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Artificial Intelligence-Based Diagnosis of Breast Cancer by Mammography Microcalcification

This study introduces a deep-learning system for rapid, automated detection and classification of tiny calcium deposits (microcalcifications) in mammograms to aid early breast cancer diagnosis. Leveraging a multi-center dataset of 4,810 biopsy-confirmed mammograms, our pipeline uses a Faster RCNN model with a feature-pyramid backbone to detect and classify microcalcifications--the pipeline requires no hand-tuned rules and provides both the overall cancer risk and highlighted lesion regions in seconds per image. On unseen test data, it achieved overall classification accuracy of 72% for discriminating between benign and malignant breasts and 78% sensitivity of malignant breast cancer prediction, marking a significant step toward AI-assisted, cost-effective breast-cancer screening that can run on standard radiology workstations.

May 13, 2025


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