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ASTRO updates guideline on radiation therapy for high-grade diffuse glioma, the most common primary brain tumor in adults

A new clinical guideline from the American Society for Radiation Oncology (ASTRO) focuses on the use of radiation therapy to treat adult patients with World Health Organization (WHO) grade 4 diffuse gliomas, a category that includes some of the most common and most aggressive primary brain tumors. The guideline, which replaces ASTRO's 2016 guideline for glioblastoma, is published in Practical Radiation Oncology.

June 26, 2025


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