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Shorter, Less Intense Radiation-Chemo Regimen Effective for HPV-Linked Oropharyngeal Cancer, Mayo Study Shows

A Mayo Clinic study finds that a shortened, less intense course of radiation and chemotherapy after minimally invasive surgery for HPV-positive oropharyngeal squamous cell carcinoma (HPV+OPSCC) results in less toxicity, substantially lowering the rates of treatment-related side effects while maintaining high cure rates. The findings were published in The Lancet Oncology.

September 2, 2025


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