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Researchers Identify Gene That Calms the Mind and Improves Attention in Mice

Attention disorders are characterized by poor ability to filter out distractions in a busy world. Current treatments for ADHD work by stimulating brain activity. In mice, low levels of the protein Homer1 led to faster and more precise responses to cues, an indication of sharper focus. This effect was created through increased inhibition of brain activity, rather than stimulation. Thus, how quiet the brain is at rest is an important source of variation that predicts attentional performance. The findings may lead to alternate therapies that calm the mind to improve attention.

December 22, 2025


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