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Gastroesophageal Cancer: A New Risk Model for Esophagectomy Draws on the STS National Database

A nationwide, real-world analysis using the STS General Thoracic Surgery Database analyzed 16,056 adults who underwent esophagectomy for primary esophageal cancer to develop and validate a long-term all-cause mortality risk model. The study demonstrates that a stratified multivariable Cox model incorporating clinicopathologic factors, including postoperative complications, can reliably predict 1-, 5-, and 10-year survival in all types of esophagectomy patients across the American Joint Committee on Cancer 8th edition stages and neoadjuvant treatment status.

January 31, 2026


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