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News for Healthier Living

New Research Creates Blueprint for Designing T Cells to Kill

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center has uncovered new genetic rules that determine how powerful immune cells--known as CD8 killer T cells--choose between becoming long-lasting, protective defenders or slipping into exhausted, dysfunctional states. The findings reveal new strategies for sustaining immune memory while preserving the ability to fight cancer and infections, with broad implications for immunotherapy and infectious disease research.

February 5, 2026


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