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News for Healthier Living

New Study Shows How to Protect the Brain to Prevent Depression and Cognitive Impairment Caused by Whole Brain Radiotherapy

* Whole brain radiotherapy (WBRT) saves lives by treating cancer that has spread to the brain, but it also causes long-standing brain damage. * Many patients develop memory problems, thinking difficulties, and depression after WBRT. * There are currently no medicines that adequately prevent these problems of WBRT. * The research team discovered that an experimental neuroprotective drug, P7C3-A20, could protect the brain from these harmful side effects of WBRT in animal models, without impairing the ability of radiation to kill tumor cells. * If these findings translate to humans, adding a drug like P7C3-A20 to WBRT could safely and effectively preserve cognition and mood after lifesaving WBRT.

February 11, 2026


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